Browsing Konferencijų pranešimų santraukos / Conference and Meeting Abstracts by Source "FEBS Journal. 42nd Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back, Sep 10-14, 2017, Jerusalem, Israel"
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Discovery and substrate specificity of a novel nucleoside hydrolase
(FEBS Journal. 42nd Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back, Sep 10-14, 2017, Jerusalem, Israel, 2017)Modified nucleotides are present in various RNA species and are critical for folding, stability, and interaction with cellular proteins. Biosynthesis of pyrimidine nucleotides and their modified derivatives in RNA is well ... -
Synthesis of modified uracil derivatives and their potential use as prodrugs
(FEBS Journal. 42nd Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back, Sep 10-14, 2017, Jerusalem, Israel, 2017)Fluorinated derivatives of uracil and uridine can act as prodrugs in the cancer therapy. The chemical synthesis of 5-fluoroisocyto-sine and the fluorinated 20-O-methyluridine was performed. 5-Fluorouridine and 5-fluorodeoxyuridine ...