Rodyti trumpą aprašą

dc.contributor.authorTrečiokienė, Indrė
dc.contributor.authorBratčikovienė, Nomeda
dc.contributor.authorGulbinovič, Jolanta
dc.contributor.authorWettermark, Bjorn Gunnar Erik Evert
dc.contributor.authorTaxis, Katja
dc.date.accessioned2023-09-18T16:17:03Z
dc.date.available2023-09-18T16:17:03Z
dc.date.issued2022
dc.identifier.other(crossref_id)134255351
dc.identifier.urihttps://etalpykla.vilniustech.lt/handle/123456789/112725
dc.description.abstractHigh blood pressure is a major risk factor contributing to death and disability rates in the Baltic states. The aim of this study was to compare the utilization of antihypertensive medicines in Estonia, Latvia and Lithuania from 2008 to 2018. In this retrospective cross-national comparison, nationally representative wholesale data from the IQVIA National Retail Audit were analyzed. The utilization of inhibitors of the renin–angiotensin system, beta blockers, calcium channel blockers, diuretics and centrally acting antihypertensives by Defined Daily Doses per 1000 inhabitants and day (DDD/TID) was used to calculate utilization. Time series analysis was used to analyze trends. The utilization increased annually by 10.88, 8.04 and 6.42 DDD/TID in Estonia, Latvia and Lithuania, respectively, from 2008. The utilization of antihypertensive drugs in 2018 was 372, 267 and 379.5 DDD/TID, respectively. Inhibitors of the renin–angiotensin system were the most commonly used class in 2008 and 2018. From 2008, the utilization of beta blockers and fixed-dose combinations including renin–angiotensin system inhibitors increased substantially, while that of calcium channel blockers decreased. Country-specific utilization trends were noted; e.g., the utilization of centrally acting antihypertensives was 30.9 DDD/TID in Lithuania compared to 3.01 DDD/TID in Estonia and 16.17 DDD/TID in Latvia. The use of antihypertensive medicines increased over the study period, but the trends for the different drug classes differed between countries.eng
dc.formatPDF
dc.format.extentp. [1-11]
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.relation.isreferencedbyDOAJ
dc.rightsLaisvai prieinamas internete
dc.source.urihttps://talpykla.elaba.lt/elaba-fedora/objects/elaba:118357177/datastreams/MAIN/content
dc.titleTrend of antihypertensive medicine use in the Baltic States between 2008 and 2018: a retrospective cross-national comparison
dc.typeStraipsnis kitoje DB / Article in other DB
dcterms.licenseCreative Commons – Attribution – 4.0 International
dcterms.references52
dc.type.pubtypeS3 - Straipsnis kitoje DB / Article in other DB
dc.contributor.institutionUniversity of Groningen Vilniaus universitetas
dc.contributor.institutionVilniaus Gedimino technikos universitetas Vilniaus universitetas
dc.contributor.institutionVilniaus universitetas
dc.contributor.institutionUppsala University Vilniaus universitetas
dc.contributor.institutionUniversity of Groningen
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.subject.researchfieldN 001 - Matematika / Mathematics
dc.subject.researchfieldM 003 - Farmacija / Pharmacy
dc.subject.studydirectionG05 - Farmacija / Pharmacy
dc.subject.endrug utilization
dc.subject.enantihypertensives
dc.subject.enBaltic states
dcterms.sourcetitlePharmacoepidemiology
dc.description.issueno. 1
dc.description.volumevol. 22
dc.publisher.nameMDPI
dc.publisher.cityBasel
dc.identifier.doi134255351
dc.identifier.doi10.3390/pharma1010001
dc.identifier.elaba118357177


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