dc.contributor.author | Rakoczy, Katarzyna | |
dc.contributor.author | Kisielewska, Monika | |
dc.contributor.author | Sedzik, Mikolaj | |
dc.contributor.author | Jonderko, Laura | |
dc.contributor.author | Celinska, Julia | |
dc.contributor.author | Sauer, Natalia | |
dc.contributor.author | Szlasa, Wojciech | |
dc.contributor.author | Saczko, Jolanta | |
dc.contributor.author | Novickij, Vitalij | |
dc.contributor.author | Kulbacka, Julita | |
dc.date.accessioned | 2023-09-18T16:26:58Z | |
dc.date.available | 2023-09-18T16:26:58Z | |
dc.date.issued | 2022 | |
dc.identifier.other | (WOS_ID)000883889100001 | |
dc.identifier.uri | https://etalpykla.vilniustech.lt/handle/123456789/114069 | |
dc.description.abstract | Electroporation (EP) allows for the transport of molecules into the cytoplasm with significant effectiveness by forming transient pores in the cell membrane using electric pulses. This can be used for cellular transport (RE—reversible electroporation) or ablation (IRE—irreversible electroporation). The first of described options fortifies medicine with novel possibilities: electrochemotherapy (ECT), which creates promising perspectives for cancer treatment, and gene electrotransfer (GET), a powerful method of DNA delivery as well as immunogen electrotransfer. The review constitutes a comprehensive explanation of the mechanism of EP in the case of GET, its present and prospective employment in medicine, including gene delivery, vaccinations, therapy, and transfection, are also presented. | eng |
dc.format | PDF | |
dc.format.extent | p. 1-19 | |
dc.format.medium | tekstas / txt | |
dc.language.iso | eng | |
dc.relation.isreferencedby | Science Citation Index Expanded (Web of Science) | |
dc.relation.isreferencedby | Scopus | |
dc.title | Electroporation in clinical applications-the potential of gene electrotransfer and electrochemotherapy | |
dc.type | Straipsnis Web of Science DB / Article in Web of Science DB | |
dcterms.accessRights | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | |
dcterms.license | Creative Commons – Attribution – 4.0 International | |
dcterms.references | 138 | |
dc.type.pubtype | S1 - Straipsnis Web of Science DB / Web of Science DB article | |
dc.contributor.institution | Wroclaw Medical University | |
dc.contributor.institution | Vilniaus Gedimino technikos universitetas Valstybinis mokslinių tyrimų institutas Inovatyvios medicinos centras | |
dc.contributor.faculty | Elektronikos fakultetas / Faculty of Electronics | |
dc.subject.researchfield | T 001 - Elektros ir elektronikos inžinerija / Electrical and electronic engineering | |
dc.subject.researchfield | N 010 - Biologija / Biology | |
dc.subject.vgtuprioritizedfields | FM0202 - Ląstelių ir jų biologiškai aktyvių komponentų tyrimai / Investigations on cells and their biologically active components | |
dc.subject.ltspecializations | L105 - Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies | |
dc.subject.en | electroporation | |
dc.subject.en | gene delivery | |
dc.subject.en | electrovaccines | |
dc.subject.en | immunogen electrotransfer | |
dcterms.sourcetitle | Applied sciences: Electroporation Systems and Applications: Volume II | |
dc.description.issue | iss. 21 | |
dc.description.volume | vol. 12 | |
dc.publisher.name | MDPI | |
dc.publisher.city | Basel | |
dc.identifier.doi | 000883889100001 | |
dc.identifier.doi | 2-s2.0-85141856089 | |
dc.identifier.doi | 85141856089 | |
dc.identifier.doi | 1 | |
dc.identifier.doi | 141792305 | |
dc.identifier.doi | 10.3390/app122110821 | |
dc.identifier.elaba | 147331828 | |