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dc.contributor.authorMelvydas, Vytautas Boleslovas
dc.contributor.authorBružauskaitė, Ieva
dc.contributor.authorGedminienė, Genovaitė
dc.contributor.authorŠiekštelė, Rimantas
dc.date.accessioned2023-09-18T16:40:01Z
dc.date.available2023-09-18T16:40:01Z
dc.date.issued2016
dc.identifier.issn0046-8991
dc.identifier.other(BIS)VGT02-000032090
dc.identifier.urihttps://etalpykla.vilniustech.lt/handle/123456789/115706
dc.description.abstractIt was determined that Kx strains secrete an X factor which can inhibit all known Saccharomyces cerevisiae killer toxins (K1, K2, K28) and some toxins of other yeast species—the phenomenon not yet described in the scientific literature. It was shown that Kx type yeast strains posess a killer phenotype producing small but clear lysis zones not only on the sensitive strain α′1 but also on the lawn of S. cerevisiae K1, K2 and K28 type killer strains at temperatures between 20 and 30 °C. The pH at which killer/antikiller effect of Kx strain reaches its maximum is about 5.0–5.2. The Kx yeast were identified as to belong to S. cerevisiae species. Another newly identified S. cerevisiae killer strain N1 has killer activity but shows no antikilller properties against standard K1, K2 and K28 killer toxins. The genetic basis for Kx killer/antikiller phenotype was associated with the presence of M-dsRNA which is bigger than M-dsRNA of standard S. cerevisiae K1, K2, K28 type killer strains. Killer and antikiller features should be encoded by dsRNA. The phenomenon of antikiller (inhibition) properties was observed against some killer toxins of other yeast species. The molecular weight of newly identified killer toxins which produces Kx type strains might be about 45 kDa.eng
dc.formatPDF
dc.format.extentp. 335-343
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.relation.isreferencedbyBIOSIS Previews
dc.relation.isreferencedbyScience Citation Index Expanded (Web of Science)
dc.relation.isreferencedbyScopus
dc.source.urihttp://link.springer.com/article/10.1007/s12088-016-0589-1
dc.subjectFM01 - Biokatalitinių procesų modeliavimas / Modelling of biocatalytic processes
dc.titleA novel Saccharomyces cerevisiae killer strain secreting the X factor related to killer activity and inhibition of S. cerevisiae K1, K2 and K28 killer toxins
dc.typeStraipsnis Web of Science DB / Article in Web of Science DB
dcterms.references31
dc.type.pubtypeS1 - Straipsnis Web of Science DB / Web of Science DB article
dc.contributor.institutionGamtos tyrimų centras
dc.contributor.institutionValstybinis mokslinių tyrimų institutas Inovatyvios medicinos centras
dc.contributor.institutionVilniaus Gedimino technikos universitetas
dc.contributor.institutionVilniaus universitetas
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.subject.researchfieldN 004 - Biochemija / Biochemistry
dc.subject.ltspecializationsL105 - Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies
dc.subject.enKiller/antikiller activity
dc.subject.enInteraction
dc.subject.enDsRNA
dc.subject.enSaccharomyces cerevisiae
dc.subject.enX factor
dc.subject.enStandard toxin inhibition
dcterms.sourcetitleIndian journal of microbiology
dc.description.issueiss. 3
dc.description.volumeVol. 56
dc.publisher.nameSpringer
dc.publisher.cityNew York
dc.identifier.doi000378709900011
dc.identifier.doi10.1007/s12088-016-0589-1
dc.identifier.elaba17168894


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