dc.contributor.author | Urbonavičius, Jaunius | |
dc.contributor.author | Meškys, Rolandas | |
dc.contributor.author | Grosjean, Henri | |
dc.date.accessioned | 2023-09-18T20:28:22Z | |
dc.date.available | 2023-09-18T20:28:22Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1355-8382 | |
dc.identifier.other | (BIS)VUB02-000051874 | |
dc.identifier.uri | https://etalpykla.vilniustech.lt/handle/123456789/150019 | |
dc.description.abstract | The peculiar methyltransferase aTrm5a catalyzes two distinct reactions: N1-methylation of guanosine and C7-methylation of 4-demethylwyosine (imG-14) that allows the production of isowyosine (imG2), an intermediate in the 7-methylwyosine (mimG) biosynthetic pathway. This bifunctional tRNA methyltransferase that acts on two chemically distinct guanosine derivatives located at the same position of tRNAPhe is unique to certain archaea and has no homologs in eukaryotes. | eng |
dc.format | PDF | |
dc.format.extent | p. 747-753 | |
dc.format.medium | tekstas / txt | |
dc.language.iso | eng | |
dc.relation.isreferencedby | Embase | |
dc.relation.isreferencedby | Scopus | |
dc.relation.isreferencedby | Elsevier Biobase | |
dc.relation.isreferencedby | CABI Abstracts Databases | |
dc.relation.isreferencedby | MEDLINE | |
dc.relation.isreferencedby | BIOSIS Previews | |
dc.relation.isreferencedby | Science Citation Index Expanded (Web of Science) | |
dc.source.uri | http://rnajournal.cshlp.org/content/20/6/747.full.pdf+html | |
dc.subject | FM01 - Biokatalitinių procesų modeliavimas / Modelling of biocatalytic processes | |
dc.title | Biosynthesis of wyosine derivatives in tRNAPhe of Archaea: role of a remarkable bifunctional tRNAPhe:m1G/imG2 methyltransferase | |
dc.type | Straipsnis Web of Science DB / Article in Web of Science DB | |
dcterms.references | 45 | |
dc.type.pubtype | S1 - Straipsnis Web of Science DB / Web of Science DB article | |
dc.contributor.institution | Vilniaus universitetas Université Paris-Sud 11, France Vilniaus Gedimino technikos universitetas | |
dc.contributor.institution | Vilniaus universitetas | |
dc.contributor.institution | Université Paris-Sud 11, France | |
dc.contributor.faculty | Fundamentinių mokslų fakultetas / Faculty of Fundamental Sciences | |
dc.subject.researchfield | N 004 - Biochemija / Biochemistry | |
dc.subject.ltspecializations | L105 - Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies | |
dc.subject.en | Transfer RNA | |
dc.subject.en | Modification | |
dc.subject.en | Methyltransferase | |
dc.subject.en | Archaea | |
dc.subject.en | COG2520 | |
dcterms.sourcetitle | RNA | |
dc.description.issue | iss. 6 | |
dc.description.volume | Vol. 20 | |
dc.publisher.name | Cold Spring Harbor Laboratory Press | |
dc.publisher.city | New York | |
dc.identifier.doi | VGT02-000028570 | |
dc.identifier.doi | 000359666804415 | |
dc.identifier.doi | 10.1261/rna.043315.113 | |
dc.identifier.elaba | 6151347 | |