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Probing of some compounds as anti-aggregatory additives in the protein refolding process from Escherichia coli inclusion bodies

dc.contributor.authorŽilinskas, Albinas
dc.contributor.authorSereikaitė, Jolanta
dc.date.accessioned2023-09-18T20:28:29Z
dc.date.available2023-09-18T20:28:29Z
dc.date.issued2011
dc.identifier.issn0885-4513
dc.identifier.other(BIS)VUB02-000041952
dc.identifier.urihttps://etalpykla.vilniustech.lt/handle/123456789/150080
dc.description.abstractFive compounds of different chemical structure were tested for aggregation suppression during the refolding of porcine and mink growth hormones as model proteins from Escherichia coli inclusion bodies by the dilution method. Of all compounds tested in this work, 3-guanidinopropionic acid (GPA) containing a guanidinium group was the most effective additive for aggregation suppression. Anti-aggregatory properties of GPA were compared with the ones of L-arginine.eng
dc.formatPDF
dc.format.extentp. 277-284
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.relation.isreferencedbyEmbase
dc.relation.isreferencedbyBiological Abstracts
dc.relation.isreferencedbyScopus
dc.relation.isreferencedbyBIOSIS Previews
dc.relation.isreferencedbyScience Citation Index Expanded (Web of Science)
dc.titleProbing of some compounds as anti-aggregatory additives in the protein refolding process from Escherichia coli inclusion bodies
dc.typeStraipsnis Web of Science DB / Article in Web of Science DB
dcterms.references24
dc.type.pubtypeS1 - Straipsnis Web of Science DB / Web of Science DB article
dc.contributor.institutionVilniaus universitetas Vilniaus Gedimino technikos universitetas
dc.contributor.institutionVilniaus Gedimino technikos universitetas
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.contributor.departmentChemijos ir bioinžinerijos katedra / Department of Chemistry and Bioengineering
dc.subject.researchfieldT 005 - Chemijos inžinerija / Chemical engineering
dc.subject.researchfieldN 003 - Chemija / Chemistry
dc.subject.enAggregation
dc.subject.enGrowth hormones
dc.subject.en3-guanidinopropionic acid
dc.subject.enRefolding
dcterms.sourcetitleBiotechnology and applied biochemistry
dc.description.issueno 4
dc.description.volumevol. 58
dc.publisher.nameJohn Wiley & Sons Ltd
dc.publisher.cityOxford
dc.identifier.doiVGT02-000022951
dc.identifier.doi10.1002/bab.40
dc.identifier.elaba6163866


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