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Synthesis of pyrimidine nucleoside and amino acid conjugates

dc.contributor.authorKoplūnaitė, Martyna
dc.contributor.authorButkutė, Kamilė
dc.contributor.authorMeškys, Rolandas
dc.contributor.authorTauraitė, Daiva
dc.date.accessioned2023-09-18T20:34:36Z
dc.date.available2023-09-18T20:34:36Z
dc.date.issued2020
dc.identifier.urihttps://etalpykla.vilniustech.lt/handle/123456789/151011
dc.description.abstractThe synthesis of novel pyrimidine nucleoside bioconjugates with amino acids is presented. The N4-amino acid-acylated 2′-deoxycytidine analogues, modified with various amino acids, were synthesized using a three-step synthesis and obtained in moderate overall yields. Novel amino acid-alkylated 2′-deoxycytidine derivatives were obtained during the rearrangement of amino acid-acylated derivatives that occurred during Boc deprotection.eng
dc.formatPDF
dc.format.extentp. 1-4
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.relation.isreferencedbyScience Citation Index Expanded (Web of Science)
dc.relation.isreferencedbyScopus
dc.relation.isreferencedbyChemical abstracts
dc.relation.isreferencedbyCAB
dc.relation.isreferencedbyCurrent Contents
dc.relation.isreferencedbyEI Compendex Plus
dc.relation.isreferencedbyEmbase
dc.relation.isreferencedbyScienceDirect
dc.source.urihttps://pdf.sciencedirectassets.com/271373/1-s2.0-S0040403920X00475/1-s2.0-S0040403920310972/main.pdf?X-Amz-Date=20201208T075943Z&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Signature=bd7076a19aa50ca92a43072129ff239f0cd13f65481e94a19a63ce6d8f920836&X-Amz-Credential=ASIAQ3PHCVTYVM4GKQH7%2F20201208%2Fus-east-1%2Fs3%2Faws4_request&type=client&tid=prr-aba70fa2-8976-438a-b0e7-c84711deea4e&sid=9b7b7dac492288453059aa8371869d76ebb3gxrqb&pii=S0040403920310972&X-Amz-SignedHeaders=host&X-Amz-Security-Token=IQoJb3JpZ2luX2VjEKf%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIBJ3edad0tZL21WwRgrJ30D7M5CeZKi%2Fx5eEnFRyMbKXAiEAnbYVZq5ZlfPvzyp2RVevZwBNymC2FexpjppWfsrl1lcqtAMIQBADGgwwNTkwMDM1NDY4NjUiDABipQFnTzIRX3IKayqRA0eL6t25q7OGXQw58464UhEPKYpSZD8Y8Pyf9IGNaPIfxqpxc7C4rZ0EcbZv7ylF8CYGpPKmB4%2FQI%2BkfiyL5EAHUv7PGbKk0eogMQ5Z%2F6cEzNgnlUKXrkffXkU2ICWiBhCo%2F%2Fibpo2Tqle6x%2BKGHc9m1xSyzx%2BnTQMRIRIoGx2NDC309RI9EyoW4P0Sytarzx5L%2FFoJY1orM1K%2Fw1xMFjVBZOaqv6abadW%2BEbZRWUCiWbfXPCiE7nYh%2FiAIWY76wzYH8X8XqAGwCzvz%2Fun6JB6lBXqDcJopgRLycC%2BAZDEW%2Fj%2B56crXhSbW0fkA7tapZZb8bjOK8o%2BUL0xJByIKUhJS0jyB8x%2BMM1XG9iG43OIqL7SwDYKMbMJFzbNRYu5jE6Ouz2OH0ayK6QuVMoUK0XOFGkOAjngIn6xjIw9%2BHkP76ylpNFgar%2B2VbTTBKQbBB6E2RMwOdqDvPaSIS9Wbs4Ohd01JhUBfcnHMCr8VknNUoQiMhmpybKuRNng9akOC8fG%2F3uQF0p0ZTlueFprOSUelsMLm8vP4FOusBL4jetTB0vQfyYFhN57ZbQ3AleR3WAb9mbweiqbBjtGPFvyu1uo%2BrQv%2B6GpW9FzShjEGUB8mK1cZM1LTWznjEAEPUcRkZ1IZevFfCW0N8MnE9PXZuLY9jFMA0%2BImI8FeJXl4N4rYCqgG3%2BN306ORQl3gO9uAsO3BuAZ8Vhq1oSndjUsxITmVeBBR7zThT%2FbkxsAzGTZfV%2FElbB3cos1VXRQUP7x2xszbuIPMZP1xxzF8iwBqC0cXdx3ck4D5EHE3%2BaYgmVUjiR949ju1A%2Ba%2F7Xo%2B2kg5wqMERNr1qKi4DAREYEYP20vUZy9H%2FfQ%3D%3D&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&X-Amz-Expires=300&hash=eb7a86dcd63cbb8ae99316832060ef84cfc2b6e76d6919bcb0bd1b39dd7c6f81
dc.source.urihttps://www.sciencedirect.com/science/article/pii/S0040403920310972?dgcid=author
dc.titleSynthesis of pyrimidine nucleoside and amino acid conjugates
dc.typeStraipsnis Web of Science DB / Article in Web of Science DB
dcterms.references33
dc.type.pubtypeS1 - Straipsnis Web of Science DB / Web of Science DB article
dc.contributor.institutionVilniaus universitetas
dc.contributor.institutionVilniaus universitetas Vilniaus Gedimino technikos universitetas
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.subject.researchfieldN 004 - Biochemija / Biochemistry
dc.subject.vgtuprioritizedfieldsFM0202 - Ląstelių ir jų biologiškai aktyvių komponentų tyrimai / Investigations on cells and their biologically active components
dc.subject.ltspecializationsL105 - Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies
dc.subject.enpyrimidine nucleoside
dc.subject.ennucleoside-amino acid conjugates
dc.subject.enN4-amino acid-acylated nucleosides
dc.subject.enN4-amino acid-alkylated nucleosides
dcterms.sourcetitleTetrahedron letters
dc.description.issueiss. 49
dc.description.volumevol. 61
dc.publisher.nameElsevier
dc.publisher.cityOxford
dc.identifier.doi000591773500007
dc.identifier.doi10.1016/j.tetlet.2020.152598
dc.identifier.elaba77019134


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