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Synthesis of pyrimidine nucleoside and amino acid conjugates

dc.contributor.authorKoplūnaitė, Martyna
dc.contributor.authorButkutė, Kamilė
dc.contributor.authorMeškys, Rolandas
dc.contributor.authorTauraitė, Daiva
dc.date.accessioned2023-09-18T20:34:36Z
dc.date.available2023-09-18T20:34:36Z
dc.date.issued2020
dc.identifier.urihttps://etalpykla.vilniustech.lt/handle/123456789/151011
dc.description.abstractThe synthesis of novel pyrimidine nucleoside bioconjugates with amino acids is presented. The N4-amino acid-acylated 2′-deoxycytidine analogues, modified with various amino acids, were synthesized using a three-step synthesis and obtained in moderate overall yields. Novel amino acid-alkylated 2′-deoxycytidine derivatives were obtained during the rearrangement of amino acid-acylated derivatives that occurred during Boc deprotection.eng
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dc.format.extentp. 1-4
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.relation.isreferencedbyScience Citation Index Expanded (Web of Science)
dc.relation.isreferencedbyScopus
dc.relation.isreferencedbyChemical abstracts
dc.relation.isreferencedbyCAB
dc.relation.isreferencedbyCurrent Contents
dc.relation.isreferencedbyEI Compendex Plus
dc.relation.isreferencedbyEmbase
dc.relation.isreferencedbyScienceDirect
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dc.source.urihttps://www.sciencedirect.com/science/article/pii/S0040403920310972?dgcid=author
dc.titleSynthesis of pyrimidine nucleoside and amino acid conjugates
dc.typeStraipsnis Web of Science DB / Article in Web of Science DB
dcterms.references33
dc.type.pubtypeS1 - Straipsnis Web of Science DB / Web of Science DB article
dc.contributor.institutionVilniaus universitetas
dc.contributor.institutionVilniaus universitetas Vilniaus Gedimino technikos universitetas
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.subject.researchfieldN 004 - Biochemija / Biochemistry
dc.subject.vgtuprioritizedfieldsFM0202 - Ląstelių ir jų biologiškai aktyvių komponentų tyrimai / Investigations on cells and their biologically active components
dc.subject.ltspecializationsL105 - Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies
dc.subject.enpyrimidine nucleoside
dc.subject.ennucleoside-amino acid conjugates
dc.subject.enN4-amino acid-acylated nucleosides
dc.subject.enN4-amino acid-alkylated nucleosides
dcterms.sourcetitleTetrahedron letters
dc.description.issueiss. 49
dc.description.volumevol. 61
dc.publisher.nameElsevier
dc.publisher.cityOxford
dc.identifier.doi000591773500007
dc.identifier.doi10.1016/j.tetlet.2020.152598
dc.identifier.elaba77019134


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