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dc.contributor.authorUzielienė, Ilona
dc.contributor.authorPopov, Anton
dc.contributor.authorVaičiulevičiūtė, Raminta
dc.contributor.authorKirdaitė, Gailutė
dc.contributor.authorBernotienė, Eiva
dc.contributor.authorRamanavičienė, Almira
dc.date.accessioned2023-12-22T07:07:15Z
dc.date.available2023-12-22T07:07:15Z
dc.date.issued2024
dc.identifier.issn1567-5394
dc.identifier.other(SCIDIR_EID)1-s2.0-S1567539423002220
dc.identifier.urihttps://etalpykla.vilniustech.lt/xmlui/handle/123456789/153810
dc.description.abstractPolypyrrole (Ppy) is an electroconductive polymer used in various applications, including in vitro experiments with cell cultures under electrical stimulation (ES). Ppy can be applied in various forms and most importantly, it is biocompatible with cells. Ppy specifically directs ES to cells, which makes Ppy a potential polymer for the development of novel technologies for targeted tissue regeneration. The high potential of ES in combination with different Ppy-based systems, such as hydrogels, scaffolds, or Ppy-layers is advantageous to stimulate cellular differentiation towards neurogenic, cardiac, muscle, and osteogenic lineages. Different in-house devices and the principles of ES application used to stimulate cellular functions are reviewed and summarized. The focus of this review is to observe the most relevant studies and their in-house techniques regarding the application of Ppy-based materials for the use of bone, neural, cardiac, and muscle tissue regeneration under ES. Different types of Ppy materials, such as Ppy particles, layers/films, membranes, and 3D-shaped synthetic and natural scaffolds, as well as combining Ppy with different active molecules are reviewed.eng
dc.formatPDF
dc.format.extentp. [1-15]
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.relation.isreferencedbyScience Citation Index Expanded (Web of Science)
dc.relation.isreferencedbyScopus
dc.titlePolypyrrole-based structures for activation of cellular functions under electrical stimulation
dc.typeStraipsnis Web of Science DB / Article in Web of Science DB
dcterms.references119
dc.type.pubtypeS1 - Straipsnis Web of Science DB / Web of Science DB article
dc.contributor.institutionValstybinis mokslinių tyrimų institutas Inovatyvios medicinos centras
dc.contributor.institutionValstybinis mokslinių tyrimų institutas Inovatyvios medicinos centras Vilniaus universitetas
dc.contributor.institutionValstybinis mokslinių tyrimų institutas Inovatyvios medicinos centras Vilniaus Gedimino technikos universitetas
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.subject.researchfieldN 003 - Chemija / Chemistry
dc.subject.researchfieldN 004 - Biochemija / Biochemistry
dc.subject.vgtuprioritizedfieldsFM0202 - Ląstelių ir jų biologiškai aktyvių komponentų tyrimai / Investigations on cells and their biologically active components
dc.subject.ltspecializationsL105 - Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies
dc.subject.enPolypyrrole
dc.subject.enMesenchymal stem cells
dc.subject.enElectrical stimulation
dc.subject.enIn-house devices
dcterms.sourcetitleBioelectrochemistry
dc.description.volumevol. 155
dc.publisher.nameElsevier B.V.
dc.publisher.cityLausanne
dc.identifier.doi1-s2.0-S1567539423002220
dc.identifier.doi0
dc.identifier.doi153825751
dc.identifier.doi001094497300001
dc.identifier.doi10.1016/j.bioelechem.2023.108585
dc.identifier.elaba180384694


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