Artificial lubrication of diseased human joints. Part 1
Abstract
Artificial lubrication of diseased human joints and endoprosthesis was elaborated. Theory and concepts of adaptive biotribology lubrication of arthritic joints was proposed. Optimal lubricants from the special binding complex of polymeric polivinylpyrrolidone (PVP) and biopolymeric hyaluronic acid compounds were prepared. Rheological, lubrication, friction, wear and tear properties of lubricants were investigated by biomechanical devices, vibrotribometry, ultrasonic-laser interferometry, and parharmadynamics by radioisotopic elimination of lubricants from joint cavity. Normal and rheumatoid arthritic (RA) and osteoarthritic (OA) patient's synovial fluids (120 patients) were investigated. Self-lubricated endoprosthesis construction was proposed and patented.