Production of recombinant mink growth hormone in E. coli

Abstract

Growth hormones are produced by the anterior pituitary gland of vertebrates. Apart from stimulating linear body growth, it plays an important role in variety of metabolic and physiological processes. There is almost no information on mink growth hormone (mGH), which probably could be a useful factor in mink fur production, synthesis in E.coli and future recovery of bioactive protein. It is known that mGH gene was cloned and sequenced [1,2]. We report the possibility to produce large amounts of mGH using recombinant DNA technology.