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dc.contributor.authorBalevičius, Saulius
dc.contributor.authorStankevič, Voitech
dc.contributor.authorŽurauskienė, Nerija
dc.contributor.authorStirkė, Arūnas
dc.contributor.authorBitinaitė, Aistė
dc.contributor.authorSaulė, Rita
dc.contributor.authorSaulis, Gintautas
dc.contributor.authorŠatkovskis, Eugenijus
dc.contributor.authorMaciulevičienė, Rita
dc.date.accessioned2023-09-18T19:43:24Z
dc.date.available2023-09-18T19:43:24Z
dc.date.issued2013
dc.identifier.other(BIS)VGT02-000026484
dc.identifier.urihttps://etalpykla.vilniustech.lt/handle/123456789/142623
dc.description.abstractThe nanosecond electric pulse generator based on spark-gap switch which is optically triggered by a 0.45-ns duration and 1-mJ energy laser pulse (wavelength 1062 nm) is designed for electroporation of biological cells suspended in liquid media. The system can also be triggered manually by changing the distance between the spark-gap electrodes. It is able to generate in 75-Ohm impedance transmission line near-perfect square-shape electric pulses (rise and fall times < 0.5 ns) with the duration of 10, 40, 60 or 92 ns. The maximal pulse amplitude is 12.5 kV. The main advantage of the system is the ability to generate single pulses the amplitude and duration of which can be precisely set in advance. To treat the cells, a coaxial cuvette with a 0.03-ml active volume and 1-mm distance between 28.26 mm2 square disk-shape electrodes was used. The system was tested on human erythrocytes. It was demonstrated that for the 92-ns and 40 ns, duration pulse, the amplitude required to electroporate 50% of cells was 11 kV/cm and 60 kV/cm respectively.eng
dc.format.extentp. 151-154
dc.format.mediumtekstas / txt
dc.language.isoeng
dc.source.urihttp://www.eappc-beams2012.org
dc.titleSystem for nanoporation of biological cells based on optically triggered high-voltage spark-gap switch
dc.typeStraipsnis recenzuotame konferencijos darbų leidinyje / Paper published in peer-reviewed conference publication
dcterms.references11
dc.type.pubtypeP1d - Straipsnis recenzuotame konferencijos darbų leidinyje / Article published in peer-reviewed conference proceedings
dc.contributor.institutionValstybinis mokslinių tyrimų institutas Fizinių ir technologijos mokslų centras
dc.contributor.institutionValstybinis mokslinių tyrimų institutas Fizinių ir technologijos mokslų centras Vytauto Didžiojo universitetas
dc.contributor.institutionVilniaus Gedimino technikos universitetas
dc.contributor.institutionVytauto Didžiojo universitetas
dc.contributor.facultyFundamentinių mokslų fakultetas / Faculty of Fundamental Sciences
dc.subject.researchfieldN 011 - Biofizika / Biophysics
dc.subject.researchfieldT 001 - Elektros ir elektronikos inžinerija / Electrical and electronic engineering
dc.subject.enElectrical pulses
dc.subject.enNanoporation
dc.subject.enBiological cells
dcterms.sourcetitle4th Euro-Asian pulsed power conference / 19th international conference on high-power particle beams (EAPPC 2012 / BEAMS 2012) : Karlsruhe, Germany, September 30 - October 4, 2012 : [proceedings]
dc.description.issueiss. 10
dc.description.volumeVol. 41
dc.publisher.nameKarlsruhe Institute of Technology
dc.publisher.cityKarlsruhe
dc.identifier.doiLBT02-000047575
dc.identifier.elaba4024025


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