Numerical modeling of DNA nucleotides binding process mechanics considering oscillations

Abstract

The paper deals with the process of binding of two nucleotides, which is considered part of a more complex process, such as the transfer of telomerase to the telomere region of chromosomes during cell division. The binding process is evaluated using the originally developed attraction-related energy dissipation mechanism. Energy dissipation has also been observed using a viscous damping model. Viscous damping is considered to obtain dissipative oscillations during the interaction of nucleotides, which can be part of the binding process. The work presents the dynamics of nucleotides, indicating the values of force, distance, velocity for a certain period of time.