Now showing items 1-20 of 28

    • A minimal model of haemoglobin oxygenation kinetics 

      Juška, Alfonsas (Biologija, 2004)
      A mathematical model based on the current understanding of cooperativity in oxygen binding to haemoglobin and relating the saturation curve of haemoglobin oxygenation to dissociation constants characterizing the affinities ...
    • Amperometrinių mikrobiojutiklių masyvo modeliavimas 

      Ivanauskas, Feliksas; Baronas, Romas; Kulys, Juozas; Sapagovas, Mifodijus (Lietuvos matematikos rinkinys, 2004)
      Straipsnyje pateikiamas amperometrinių mikrobiojutiklių, sudarytų fermento mikroreaktorių masyvo pagrindu, matematinis modelis dvimatėje erdvėje. Modelio pagrindas - difuzijos lygtys su netiesiniu nariu, aprašančiu fermento ...
    • Baltijos jūros pagrindinės ekologinės problemos 

      Bumelienė, Žana; Bytautas, Rolandas; Krupickaitė, Dovilė; Stuckaitė, A. (Aplinkos apsauga : Vilniaus technikos universiteto mokslo darbai, Nr. 2, 1994)
      The increase of the antrophological influence on the environment of the Baltic Sea leads to undisarable consequences. So, the Baltic States participation in pollution research is very important. One must select the right ...
    • Biologinis azoto junginių šalinimas iš nuotekų šaltuoju laikotarpiu 

      Paulionytė, Skaistė; Mažeikienė, Aušra (Mokslas - Lietuvos ateitis : Aplinkos apsaugos inžinerija = Science - Future of Lithuania : Environmental protection engineering, 2016)
      Šiandien individualių buitinių nuotekų valymo įrenginių skaičius šalyje vis didėja. Populiarūs biologinio valymo veikliojo dumblo pagrindu veikiantys įrenginiai. Beveik nėra duomenų, kaip iš nuotekų šalinami azoto junginiai, ...
    • Biosensor response at mixed enzyme kinetics and external diffusion limitation in case of substrate inhibition 

      Kulys, Juozas (Nonlinear analysis: modelling and control, 2006)
      The action of a biosensor containing non Michaelis-Menten enzyme was modeled at mixed enzyme kinetics and external diffusion limitation in the case of substrate inhibition. The calculations show that at the electrode surface ...
    • Computational modelling of a sensor based on a array of enzyme microreactors 

      Baronas, Romas; Ivanauskas, Feliksas; Kulys, Juozas; Sapagovas, Mifodijus (Nonlinear analysis: modelling and control, 2004)
      This paper presents a two-dimensional-in-space mathematical model of a sensor system based an array of enzyme microreactors immobilised on a single electrode. The system acts under amperometric conditions. The model is ...
    • Dimerization of human growth hormone in the presence of Congo red 

      Sereikaitė, Jolanta; Strainienė, Eglė; Bumelienė, Žana; Morkūnas, Mindaugas; Gedminienė, Genovaitė; Bumelis, Vladas Algirdas (Biologija, 2004)
      Absorption difference spectroscopy has been used to monitor Congo red interaction with human growth hormone. It has been shown that Congo red forms a complex with this α-protein. Formation of human growth hormone dimers ...
    • Expression of glucose dehydrogenase–synuclein hybrid in Saccharomyces Cerevisiae 

      Servienė, Elena; Pilevičienė, Simona; Lukša, Juliana (Biologija, 2010)
      Yeast expression vectors bearing glucose dehydrogenase gene fused with α-Synuclein (GDHsyn) were constructed and successfully introduced into Saccharomyces cerevisiae cells. Optimization of growing conditions of yeast ...
    • Glucose biosensor based on chitosan-gold and prussian blue-gold nanoparticles 

      Kulys, Juozas; Stupak, Robert (The open nanoscience journal, 2008)
      Amperometric glucose biosensors were constructed by codeposition of glucose oxidase (GOx) with chitosangold (chitosan-AuNP) on gold-Prussian Blue (Au-PB) nanoparticles modified glassy carbon electrodes (GCE). The high ...
    • High level expression of recombinant bovine growth hormone 

      Morkūnas, Mindaugas; Gedminienė, Genovaitė; Sereikaitė, Jolanta; Bumelienė, Žana; Bumelis, Vladas Algirdas (Biologija, 2004)
      A high level biosynthesis of bovine growth hormone (bGH) was achieved in the E. coli BL21 (DE3) strain through the construction of pET21a/bGH plasmid. The plasmid carrying a sequence of bGH was used as a DNA template. The ...
    • Initial analysis of highly competitive yeast strains promising for ethanol industry 

      Melvydas, Vytautas Boleslovas; Gedminienė, Genovaitė; Jarmalaitė, Ieva; Čapukoitienė, Brigita; Nemceva, Diana (Biologija, 2006)
      We have analyzed S. cerevisiae Rom K-100, M437, 4+, 18M, 20K++, K+ob and the newly discovered IIx31, III.2, Spanguolė yeast strains which are promising to use in alimentary (wine) industry, their efficiency of secrete ...
    • Investigation of thermal stability of recombinant human interferon-gamma 

      Bumelis, Vladas Algirdas; Bumelienė, Žana; Gedminienė, Genovaitė; Smirnovas, Vytautas; Sereikaitė, Jolanta; Medelytė, Ineta (Biologija, 2002)
      Our studies in the structure and biological function of recombinant human interferon gamma (IFN-y) showed that IFN-y was stable at -20 C if to analyse the quantity of its monomeric form (MW 17240 Da). The protein aggregated ...
    • Kinetic model of biphasic character of catalase inhibition 

      Kulys, Juozas; Kriaučiūnas, Kostas; Vidžiūnaitė, Regina (Nonlinear analysis: modelling and control, 2003)
      A mathematical model of kinetics of fungal catalase inhibition with hydroxylamine in presence of substrate (hydrogen peroxide) has been developed. The scheme includes an intermediate formation and slow reversible native ...
    • Kinetics of biocatalytical synergistic reactions 

      Kulys, Juozas (Nonlinear analysis: modelling and control, 2005)
      Kinetics of biocatalytical synergistic reactions has been analyzed at non-stationary state (NSS) and at quasi steady state (QSS) conditions. The application to the model kinetic constants taken from the first type of the ...
    • Kinetics of fungal catalases inhibition with hydroxylamine 

      Vidžiūnaitė, Regina; Kriaučiūnas, Kostas; Kulys, Juozas (Biologija, 2003)
      Inhibition of the catalase from Aspergilus niger was performed with hydroxylamine (HA). The inhibition decreased at acid pH with pKa 6.0 indicating that only the unprotonated form of HA acts as an inhibitor. Hydrazine (HZ), ...
    • Macrokinetic model of catalase electrode with biphasic enzyme inhibition 

      Kriaučiūnas, Kostas; Kulys, Juozas (Nonlinear analysis: modelling and control, 2004)
      Macrokinetics of catalase based enzyme electrode was investigated in presence of enzyme inhibitor – hydroxylamine. The modeling of the electrode was performed using biphasic scheme of enzyme inhibition and external diffusion ...
    • Medium optimization for bacteriocin production and bacterial cell growth of Geobacillus sp. 15 strain 

      Kaunietis, Arnoldas; Pranckutė, Raminta; Lastauskienė, Eglė; Čitavičius, Donaldas Jonas (Journal of Antimicrobial Agents, 2017)
      In this study we determined that Geobacillus sp. 15 strain secretes antibacterial compound-bacteriocin. Only few bacteriocin producing thermophilic bacteria of this genus have been identified to the date. Also, we optimized ...
    • Modeling and simulation of biosensors 

      Baronas, Romas; Kulys, Juozas (Encyclopedia of applied electrochemistry, 2014)
    • Modeling Enzymes inhibition during microparticles formation 

      Kulys, Juozas (Nonlinear analysis : modelling and control, 2003)
      A mathematical model of enzymes inhibition during microparticles formation has been developed. The model is based on radial substrate diffusion through diffusion layer that surrounds microparticle. The inhibition of enzymes ...
    • Modeling the enantioselective enzymatic reaction with modified genetic docking algorithm 

      Žiemys, Artūras; Kraujalienė, Lina; Kulys, Juozas (Nonlinear analysis: modelling and control, 2004)
      The handling algorithms for molecular interaction and docking is of increasing involvement in biological processes modeling. Genetic algorithm, in particular, improves the computation models and leads to more effective and ...